Antibody CMC Development Xchange - San Francisco - 2026

Downstream Processing & Purification
- Downstream Processing & Purification
15:30 16:30

Managing resin fouling and degradation while maintaining high purification efficiency

Debola Banerjee, Senior Director, Biotherapeutics CMC - Exilixis
Quality Control & Characterization
- Quality Control & Characterization
15:30 16:30

Challenges of developing stable high‐concentration formulations for novel biologic modalities
Quality Control & Characterization
- Quality Control & Characterization
09:05 10:05

Detecting variations in glycan profiles that affect efficacy or immunogenicity
Formulation & Stability
- Formulation & Stability
09:05 10:05

Choosing buffers and stabilizers that prevent aggregation and degradation
Downstream Processing & Purification
- Downstream Processing & Purification
11:10 12:10

Ensuring minimal HCP contamination to meet regulatory requirements

What are the primary sources of host cell protein (HCP) contamination throughout the manufacturing p ...
Downstream Processing & Purification
- Downstream Processing & Purification
14:55 15:25

Poster Presentation: Balancing robust viral inactivation with product recovery
Quality Control & Characterization
- Quality Control & Characterization
11:10 12:10

Resolving acidic or basic variants that may influence stability or bioactivity

Which acidic and basic variants are present, and what are their underlying root causes (e.g., deamid ...
Cell Line Development
- Cell Line Development
11:10 12:10

Balancing productivity with quality: Are we reaching the limits of cell line optimisation?

Are current cell line optimisation strategies approaching their biological or technological limits? ...
Quality Control & Characterization
- Quality Control & Characterization
14:55 15:25

Poster Presentation: Establishing reliable in vitro assays for antibody activity
Formulation & Stability
- Formulation & Stability
11:10 12:10

Accurately forecasting long-term stability from accelerated data

How reliably can accelerated stability studies predict long-term product behavior under real-time co ...
Formulation & Stability
- Formulation & Stability
15:30 16:30

Identifying conditions that trigger denaturation or chemical modifications
Upstream Development
- Upstream Development
11:10 12:10

Balancing nutrient supply to maximize productivity without affecting product quality

How can nutrient supply be optimized to maximize cell growth and productivity without compromising p ...
Upstream Development
- Upstream Development
15:30 16:30

How can we accomplish early upstream development while racing to FIH?

Toya Baral, Senior Director - Chantibody
Formulation & Stability
- Formulation & Stability
14:55 15:25

Poster Presentation: Preventing loss of activity or aggregation during storage and shipping
Upstream Development
- Upstream Development
14:55 15:25

Poster Presentation: Balancing robust viral inactivation with product recovery
Cell Line Development
- Cell Line Development
14:55 15:25

Poster Presentation: Accelerating development timelines: Can automation and AI truly transform cell line screening?
Downstream Processing & Purification
- Downstream Processing & Purification
09:05 10:05

Separating aggregates and fragments without reducing yield or affecting stability

Sharat Varma, Director - Sutro Biopharma
Cell Line Development
- Cell Line Development
15:30 16:30

From lab to manufacturing: How do we ensure cell lines are adaptable to evolving processes at scale?
Upstream Development
- Upstream Development
09:05 10:05

Developing a high-throughput early developability package to support the pipeline and AI model training Topic TBC

Tatjana Petojevic, Director, Head of Protein Sciences - Rondo Therapeutics
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
13:10 13:40

Spotlight Presentation:
Cell Line Development
- Cell Line Development
09:05 10:05

Cell line development strategies towards overcoming multispecific expression challenges
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
16:30 17:30

Drinks-Canape Reception
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
14:45 14:55

Afternoon Refreshments
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
13:45 14:15

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
14:15 14:45

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
12:10 13:10

Networking Lunch
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
11:00 11:10

Morning Refreshments
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
10:30 11:00

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
10:05 10:30

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
08:30 09:00

Opening Address & Keynote Presentation:
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
08:00 08:30

Registration