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Separating aggregates and fragments without reducing yield or affecting stability

01 Sept 2026
Downstream Processing & Purification
  • Selecting purification technologies (SEC, IEX, HIC, membrane-based approaches) that balance purity, scalability, and throughput.
  • Preventing process-induced aggregation or fragmentation during purification and concentration steps.
  • Maintaining long-term product stability after removal of aggregates/fragments.
Industry Expert
Debola Banerjee, Senior Director, Biotherapeutics CMC - Exelixis