Antibody Manufacturing Xchange - Boston - 2026

Quality Control & Characterization
- Quality Control & Characterization
15:30 16:30

Challenges of developing stable high‐concentration formulations for novel biologic modalities

What issues are you faced with when developing high concentration formulations for novel modalities? ...

Dmitry Gumerov, Senior Director, CMC, Pharmaceutical Sciences and Technology - Visterra Inc. (Otsuka company)
Quality Control & Characterization
- Quality Control & Characterization
09:05 10:00

Detecting variations in glycan profiles that affect efficacy or immunogenicity

Shannon Renn, Director Analytical Development - Celldex Therapeutics
Formulation & Stability
- Formulation & Stability
09:05 10:00

Choosing buffers and stabilizers that prevent aggregation and degradation [Topic TBC]

Satish Singh, Vice President, Drug Product Development - Astria Therapeutics
Downstream Processing & Purification
- Downstream Processing & Purification
11:10 12:10

Ensuring minimal HCP contamination to meet regulatory requirements
Downstream Processing & Purification
- Downstream Processing & Purification
14:55 15:25

Poster Presentation: Balancing robust viral inactivation with product recovery
Quality Control & Characterization
- Quality Control & Characterization
11:10 12:10

Resolving acidic or basic variants that may influence stability or bioactivity
Cell Line Development
- Cell Line Development
11:10 12:10

Balancing productivity with quality: Are we reaching the limits of cell line optimisation?
Quality Control & Characterization
- Quality Control & Characterization
14:55 15:25

Poster Presentation: Establishing reliable in vitro assays for antibody activity
Formulation & Stability
- Formulation & Stability
11:10 12:10

Accurately forecasting long-term stability from accelerated data
Formulation & Stability
- Formulation & Stability
15:30 16:30

Identifying conditions that trigger denaturation or chemical modifications
Downstream Processing & Purification
- Downstream Processing & Purification
15:30 16:30

Managing resin fouling and degradation while maintaining high purification efficiency
Upstream Development
- Upstream Development
11:10 12:10

Balancing nutrient supply to maximize productivity without affecting product quality
Upstream Development
- Upstream Development
15:30 16:30

Minimizing formation of non-functional antibodies during production

Rustin Shenkman, Director, Internal Cell Culture Development & Manufacture - Kiniksa Pharmaceuticals
Formulation & Stability
- Formulation & Stability
14:55 15:25

Poster Presentation: Preventing loss of activity or aggregation during storage and shipping
Upstream Development
- Upstream Development
14:55 15:25

Poster Presentation: Maintaining consistent growth and antibody quality from lab-scale to commercial-scale bioreactors
Cell Line Development
- Cell Line Development
14:55 15:25

Poster Presentation: Balancing productivity with quality: Are we reaching the limits of cell line optimisation?
Downstream Processing & Purification
- Downstream Processing & Purification
09:05 10:00

Separating aggregates and fragments without reducing yield or affecting stability Topic TBC

Deborah Moore-Lai, Vice President of Protein Sciences - ProFound Therapeutics
Cell Line Development
- Cell Line Development
15:30 16:30

From lab to manufacturing: How do we ensure cell lines are adaptable to evolving processes at scale?

How can we ensure consistency in genetic integrity when implementing updated or intensified processe ...

Christina Alves - Takeda
Upstream Development
- Upstream Development
09:05 10:00

Developing a high-throughput early developability package to support the pipeline and AI model training

How can we meet the growing demand for early developability assessment across expanding pipelines? W ...

Gilad Kaplan, Director of Protein Analytics and Developability for Biologics Engineering, R&D team lead - AstraZeneca
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
13:10 13:40

Spotlight Presentation:
Cell Line Development
- Cell Line Development
09:05 10:00

Cell line development strategies towards overcoming multispecific expression challenges

What attributes make multispecific antibodies a promising emerging class of therapeutic modalities? ...

Jack Scarcelli, Senior Director, Head of Cell Line Development - Sanofi
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
16:30 17:30

Drinks-Canape Reception
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
14:45 14:55

Afternoon Refreshments
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
13:45 14:15

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
14:15 14:45

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
12:10 13:10

Networking Lunch
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
11:00 11:10

Morning Refreshments
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
10:30 11:00

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
10:05 10:30

1-2-1 Meetings / Networking Break
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
08:30 09:00

Opening Address & Keynote Presentation:
- Cell Line Development
- Upstream Development
- Downstream Processing & Purification
- Formulation & Stability
- Quality Control & Characterization
08:00 08:30

Registration