Overcoming fragmentation between cell line development, media optimization, and process design in upstream development
29 Apr 2026
Upstream Development
- How are you breaking down silos between cell line development, media strategy, and process development?
- Are we still treating cell line development and media optimization too independently?
- How has the role of media evolved—from a supporting component to a strategic lever?
- Where are you seeing real impact from AI/ML in media and process optimization today?
- How early are you designing upstream processes with commercial scale in mind?
- Where does intensification deliver the most value—and where does it introduce complexity?
- What does an ideal upstream partner look like across CLD, media, and process development?
- Will upstream development become largely predictive and standardized, or remain highly empirical?



