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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
Strategic application of advanced analytical techniques can help improve selection of candidates and
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Quality Control
How can QC teams detect and quantify raw material and intermediate variability before it impacts cri
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Novel Modalities & Discovery
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Novel Modalities & Discovery
The search for therapeutic nucleic acids has historically been dominated by serendipity and high-thr
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CMC & Process Development
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CMC & Process Development
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Drug Delivery
Which imaging modalities provide the most meaningful insight into tissue distribution and intracellu
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Drug Delivery
Key CNS Receptors: TfR and Emerging Targets Design Principles: Binder, Linker, and Payload Systemic
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Quality Control
This session will focus specifically on the role of automation and digital systems in improving cons
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CMC & Process Development
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CMC & Process Development
Extrahepatic oligonucleotide programs introduce distinct CMC challenges that differ from established
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CMC & Process Development
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CMC & Process Development
Analytical techniques, considerations and gaps supporting oligonucleotide and oligonucleotide-conjug
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Quality Control
Framing the bottleneck: Align on the most common purification failure points after the generation of
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Novel Modalities & Discovery
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Novel Modalities & Discovery
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Quality Control
How can QC strategies evolve to support increasing sequence diversity and chemical complexity in oli
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Drug Delivery
Beyond hepatic delivery with GalNAc, what ligand technologies hold the most promise (e.g. antibodies
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
Afternoon Refreshments
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
Evening Drinks Reception
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Drug Delivery
Peptide and oligonucleotide therapeutics present distinct development challenges, including tissue p
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
1-2-1 Meetings/Networking Break
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
Preclinical development and IND milestones are often measured by speed to market, supported by toxic
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
1-2-1 Meetings/Networking Break
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
Networking Lunch
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Novel Modalities & Discovery
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Novel Modalities & Discovery
How can early discovery teams better predict human translation for novel backbone chemistries and co
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
Morning Refreshments
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
1-2-1 Meetings/Networking Break
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
1-2-1 Meetings/Networking Break
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Novel Modalities & Discovery
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Drug Delivery
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CMC & Process Development
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Quality Control
Registration
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CMC & Process Development
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CMC & Process Development
Overview of current and advanced delivery technologies such as LNP, AAV, conjugations, polymeric etc
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Novel Modalities and Discovery
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Novel Modalities & Discovery
On the evolutionary path: What's been done so far in optimizing naturally occurring ligands (GLP-1 d
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