Oligonucleotide Therapeutics Xchange - Maryland - 2024

Manufacturing
- Manufacturing
09:05 10:05

Novel cost-effective manufacturing mechanisms for synthetic oligonucleotides

Simion Viorel, Director of Immunology - Sail Biomedicines
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
16:50 17:50

Drinks-Canape Reception
Manufacturing
- Manufacturing
15:50 16:50

Novel approaches to manufacturing RNA-based vaccines

Nicholas Manzo, Director, CMC RNA Vaccines - Seqirus
New Modalities
- New Modalities
15:50 16:50

Overcoming challenges in synthetic oligonucleotide silenced chromosome reactivation

David Blackmon, Director - Alcyone Therapeutics
Drug Delivery
- Drug Delivery
09:05 10:05

Novel approaches to delivering RNA-based vaccines

Lorena Parlea, Expert Scientist - RNA Vaccines - GSK
Manufacturing
- Manufacturing
15:15 15:45

Poster Presentation: Untargeted Mass Spectrometry for Precision Oligo Analytics

This session on the Manufacturing Track will cover the use of untargeted mass spectrometry for oligo ...

Joseph Fraone, Business Development Manager - Bachem
Oligonucleotide Discovery
- Oligonucleotide Discovery
15:15 15:45

Poster Presentation: Thiophosphoramidate Morpholino Oligonucleotides (TMOs): A Novel Class of PMOs compatible With Conventional Automated Oligonucleotide Synthesis

Jeremy Little, Director of Custom Oligonucleotides - ChemGenes
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
15:05 15:15

Afternoon Refreshments
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
14:35 15:05

1-2-1 Meetings / Networking Break
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
14:00 14:30

1-2-1 Meetings / Networking Break
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
13:25 13:55

Spotlight Presentation: Eco-Friendly Oligonucleotide Manufacturing Through Hybrid Fragment Synthesis, Biocatalytic Ligation, and Continuous Processing

The presentation will focus on sustainable oligonucleotide production achieved through strategic inv ...

Charles E. Chase Ph.D., Vice President, Technical Business Development - Asymchem
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
12:25 13:25

Networking Lunch
Manufacturing
- Manufacturing
11:25 12:25

Current challenges for drug substance CDMOs in the Oligonucleotide space

What are the timeline and scale expectations? What is important when selecting your CMO? How importa ...

Trishul Shah, Director Business Development, Head of Sales North America - PolyPeptide
New Modalities
- New Modalities
11:25 12:25

[Manufacturing topic] Manufacturing n-of-1 batches - helping 1 patient at a time?

Jeremy Little, Director of Custom Oligonucleotides - ChemGenes
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
11:15 11:25

Morning Refreshments
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
10:45 11:15

1-2-1 Meetings / Networking Break
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
10:10 10:40

1-2-1 Meetings / Networking Break
Oligonucleotide Discovery
- Oligonucleotide Discovery
09:05 10:05

Designing mRNA to induce an increasingly robust immune response

Optimizing mRNA Stability and Translation Efficiency Targeted Delivery and Uptake by Immune Cells Ba ...

Weiguo Zhai, Senior Director, R&D Analytical Sciences, BioPharmaceutical Development - AstraZeneca
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
08:30 09:00

Opening Address & Keynote Presentation: ChemGenes
- New Modalities
- Oligonucleotide Discovery
- Manufacturing
- Drug Delivery
08:00 08:30

Registration