Oligonucleotide Therapeutics Xchange - Maryland - 2024

Manufacturing
- Manufacturing
09:05 10:05

Novel cost-effective manufacturing mechanisms for synthetic oligonucleotides

Simion Viorel, Director of Immunology - Sail Biomedicines
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
16:50 17:50

Drinks-Canape Reception
New Modalities
- New Modalities
15:50 16:50

Overcoming challenges in synthetic oligonucleotide silenced chromosome reactivation

David Blackmon, Director - Alcyone Therapeutics
Manufacturing
- Manufacturing
15:50 16:50

Novel approaches to manufacturing RNA-based vaccines

Lorena Parlea, Expert Scientist - RNA Vaccines - GSK
Manufacturing
- Manufacturing
15:15 15:45

Poster Presentation: Untargeted Mass Spectrometry for Precision Oligo Analytics

This session on the Manufacturing Track will cover the use of untargeted mass spectrometry for oligo ...

Joseph Fraone, Business Development Manager - Bachem
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
15:05 15:15

Afternoon Refreshments
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
14:35 15:05

1-2-1 Meetings / Networking Break
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
14:00 14:30

1-2-1 Meetings / Networking Break
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
13:25 13:55

Spotlight Presentation: Thiophosphoramidate Morpholino Oligonucleotides (TMOs): A Novel Class of PMOs compatible With Conventional Automated Oligonucleotide Synthesis

Yann Thillier, PhD,, Senior Scientist - ChemGenes
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
12:25 13:25

Networking Lunch
Manufacturing
- Manufacturing
11:25 12:25

Current challenges for drug substance CDMOs in the Oligonucleotide space

What are the timeline and scale expectations? What is important when selecting your CMO? How importa ...

Trishul Shah, Director Business Development, Head of Sales North America - PolyPeptide
New Modalities
- New Modalities
11:25 12:25

[Manufacturing topic] Manufacturing n-of-1 batches - helping 1 patient at a time?

Jeremy Little, Director of Custom Oligonucleotides - ChemGenes
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
11:15 11:25

Morning Refreshments
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
10:45 11:15

1-2-1 Meetings / Networking Break
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
10:10 10:40

1-2-1 Meetings / Networking Break
Oligonucleotide Discovery
- Oligonucleotide Discovery
09:05 10:05

Designing mRNA to induce an increasingly robust immune response

Optimizing mRNA Stability and Translation Efficiency Targeted Delivery and Uptake by Immune Cells Ba ...

Ravinder Earla, Associate Director - Aviceda Therapeutics
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
08:30 09:00

Opening Address & Keynote Presentation: Eco-friendly oligonucleotide manufacturing through hybrid fragment synthesis, biocatalytic ligation, and continuous processing

Charles E. Chase Ph.D., Vice President, Technical Business Development - Asymchem
- Oligonucleotide Discovery
- Drug Delivery
- New Modalities
- Manufacturing
08:00 08:30

Registration