Spotlight Presentation: Eco-Friendly Oligonucleotide Manufacturing Through Hybrid Fragment Synthesis, Biocatalytic Ligation, and Continuous Processing
30 Oct 2024
New Modalities
,
Oligonucleotide Discovery
,
Manufacturing
,
Drug Delivery
)
The presentation will focus on sustainable oligonucleotide production achieved through strategic investments in a hybrid SPOS/LPOS fragment-based approach combined with directed enzyme evolution, enzymatic ligation, and continuous processing. Complex oligonucleotides are manufactured with increased efficiency, enhanced quality, and reduced environmental impact, all while ensuring competitive manufacturing costs.
