Oligonucleotide Therapeutics Xchange - Boston - 2024

Manufacturing
- Manufacturing
15:50 16:50

Novel methodologies to manufacture Oligonucleotides

Mayur Patel, Director, Oligonucleotides Chemistry - Korro bio
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
15:05 15:15

Afternoon Refreshments
Drug Delivery
- Drug Delivery
11:25 12:25

Manufacturing n-of-1 batches ' helping 1 patient at a time? [Manufacturing Topic]

Jeremy Little, Director, Oligonucleotide Business Unit - ChemGenes
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
16:50 17:50

Evening Drinks Reception
Oligonucleotide Discovery
- Oligonucleotide Discovery
15:50 16:50

Emerging opportunities for liver-targeting and extrahepatic areas.

Lakshmi Bhagat, Associate Scientific Director - Luye Pharma Group
New Modalities
- New Modalities
15:50 16:50

Novel new modalities for oligonucleotides.

Dan Roseman, Associate Director, Analytical CMC Strategy - Bristol-Myers Squibb
Manufacturing
- Manufacturing
15:15 15:45

Poster Session: Untargeted Mass Spectrometry for Precision Oligo Analytics

Sumukh Ray, Principal Scientist, Analytical Development - Bachem
Oligonucleotide Discovery
- Oligonucleotide Discovery
15:15 15:45

Poster Session: XNA-Hub: The First Worldwide Experimentally-Calibrated in-silico Platform to Model and Investigate Natural and Non-Natural Nucleic Acids

Vito Genna, Director of Nucleic Acids Department - Nostrum Biodiscovery
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
13:25 13:55

Spotlight Presentation: mRNA Technology Challenge and Process Scheme

Tianqi Min, Director - Vazyme
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
14:35 15:05

1-2-1 Meetings/Networking Break
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
14:00 14:30

1-2-1 Meetings/Networking Break
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
12:25 13:25

Networking Lunch
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
08:30 09:00

Opening Address & Keynote Presentation: Thiophosphoramidate Morpholino Oligonucleotides: A novel class of PMOs compatible with conventional automated ON synthesis.
New Modalities
- New Modalities
11:25 12:25

Strategies for Production of Oligonucleotide Conjugates [Manufacturing Topic]

Effect of conjugation site on process Impact of conjugate on chromatography Analytical implications

Benjamin Thompson, Ph.D., Process Development Project Leader - Nitto Avecia
Manufacturing
- Manufacturing
11:25 12:25

Current challenges for drug substance CDMOs in the Oligonucleotide space.

Trishul Shah, Global Director and Head of Sales - PolyPeptide
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
11:15 11:25

Morning Refreshments
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
10:45 11:15

1-2-1 Meetings/Networking Break
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
10:10 10:40

1-2-1 Meetings/Networking Break
Oligonucleotide Discovery
- Oligonucleotide Discovery
09:05 10:05

Novel oligonucleotide drug delivery approaches.

Harsh Chauhan, Director, Formulation Development and External Manufacturing - Alltrna
- Oligonucleotide Discovery
- New Modalities
- Drug Delivery
- Manufacturing
08:00 08:30

Registration
New Modalities
- New Modalities
09:05 10:05

New formats / chemical modifications for antisense therapeutics

Vinod Vathipadiekal, Board Director - Aldebaran Therapeutics
Drug Delivery
- Drug Delivery
09:05 10:05

How to speed up oligonucleotide drug candidates selection
Manufacturing
- Manufacturing
09:05 10:05

Downstream manufacturing challenges for synthetic oligonucleotides.

Firoz Antia, Executive Director, Head of Oligonucleotide Development - Biogen