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Welcome to hubXchange's Oligonucleotide & Peptides Xchange San Francisco 2026.

This event brings together senior-level scientists and executives from the pharmaceutical and biotech sectors to tackle key challenges in Novel Modalities and Discovery, Drug Delivery, CMC & Process Development, and Quality Control.

Attendees can engage in roundtable discussions, pre-booked 1:1 meetingspresentations, and networking sessions with top industry experts, to foster collaboration and find innovative solutions to accelerate Oligonucleotides.

Take advantage of this unique highly interactive meeting format designed for maximum engagement, collaboration, and networking.

San Francisco | 3rd September 2026 | 08:00am - 6:15pm

VIEW AGENDA    REGISTER FOR FREE   OUR PARTNERS    EVENT INFORMATION

Why choose hubXchange?

FULL AGENDA

Click the topic titles to find out more!

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08:00
  1. Registration
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
08:30
  1. Opening Address & Keynote Presentation: The Overlooked Oligo: Why PNA Deserves a Closer Look in Your Pipeline
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    Discover where the oligonucleotide field is headed and uncover the opportunities that are often overlooked. This presentation explores why peptide nucleic acids (PNAs) are gaining renewed attention, h ...
09:05
  1. Novel Modalities & Discovery
    60 mins
    • Novel Modalities & Discovery
    How can we accurately predict human bio-distribution and organ-specific target engagement from early non-human primate (NHP) or in vitro models? What are the most reliable pharmacodynamic (PD) and sol ...
  2. Drug Delivery
    60 mins
    • Drug Delivery
    Do you view whole brain distribution, cellular uptake or endosomal escape as the dominant bottleneck to achieving maximal efficacy for CNS-targeted nucleic acid therapies? Getting ASOs to deeper brain ...
  3. CMC & Process Development
    60 mins
    • CMC & Process Development
    Goal: To establish a cross-functional framework that aligns discovery scientists and CMC engineers on the minimum viable data set required to "greenlight" a novel modality for clinical development. Br ...
10:10
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
10:40
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
11:10
  1. Morning Refreshments
    10 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
11:20
  1. Drug Delivery
    60 mins
    • Drug Delivery
    Overcoming the Endosomal Escape Bottleneck; increasing therapeutic efficacy by dictating intracellular trafficking Blood-Brain Barrier (BBB) Penetration & Transcytosis; challenges in effective use of ...

    Pace Life Sciences

  2. CMC & Process Development
    60 mins
    • CMC & Process Development
    As demand for life-saving nucleic acid therapeutics surges, there is a push in the industry to actively transition from legacy phosphoramidite chemistry to more sustainable manufacturing paradigms. Tr ...

    ChemGenes

12:20
  1. Networking Lunch
    60 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
13:20
  1. Spotlight Presentation: Analytical Characterization of Oligonucleotides
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    Strategic application of advanced analytical techniques can help improve selection of candidates and guide development decisions, leading to a greater number of safer, more efficacious therapies succe ...
13:55
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
14:25
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
14:55
  1. Afternoon Refreshments
    10 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
15:05
  1. 1-2-1 Meetings / Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
15:40
  1. Novel Modalities & Discovery
    30 mins
    • Novel Modalities & Discovery
    Nostrum Biodiscovery advances therapeutic discovery by seamlessly blending high-resolution, physics-based molecular modeling with advanced machine learning. Delivering built-in quantum accuracy, Nostr ...

    Nostrum Bio

  2. Drug Delivery
    30 mins
    • Drug Delivery
    The growing demand for siRNA therapeutics is driving the need for more efficient and scalable manufacturing strategies. Enzymatic ligation has emerged as a promising approach for joining chemically sy ...

    Ajinomoto Bio-Pharma Services

  3. CMC & Process Development
    30 mins
    • CMC & Process Development

    ChemGenes

16:15
  1. Novel Modalities & Discovery
    60 mins
    • Novel Modalities & Discovery
    How are pharmaceutical companies moving beyond AI for prediction toward AI for decision-making? What role do human genetics and multimodal data play in improving target confidence and translational su ...
  2. Drug Delivery
    60 mins
    • Drug Delivery
    When the screening model, not the molecule, is the problem - In vitro potency under transfection or free uptake often fails to predict extrahepatic delivery in vivo. How do we choose discovery models ...
  3. CMC & Process Development
    60 mins
    • CMC & Process Development
    How can QC teams detect and quantify raw material and intermediate variability before it impacts critical quality attributes of the final product What analytical controls are most effective for monito ...
17:15
  1. 60 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development

 

EVENT INFORMATION

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DATES

San Francisco
Sept 3, 2026

Thursday 3rd September 2026

 

DoubleTree by Hilton San Francisco Airport Hotel Photo

 

VENUE

 

DoubleTree by Hilton San Francisco Airport Hotel

DoubleTree by Hilton
San Francisco Airport Hotel
835 Airport Blvd, Burlingame
California, 94010-9949

MAP

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EVENT PARTNERS

REGISTRATION FORM

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Complimentary Registration is only available for Senior Scientists & above, in Pharma & Bio Tech, with an active drug pipeline.
 

For Service Providers, please click here.