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Welcome to hubXchange's Oligonucleotide & Peptides Xchange Boston 2026.

This event brings together senior-level scientists and executives from the pharmaceutical and biotech sectors to tackle key challenges in Novel Modalities & Discovery, Drug Delivery, CMC & Process Development, and Quality Control.

Attendees can engage in roundtable discussions, pre-booked 1:1 meetingspresentations, and networking sessions with top industry experts, to foster collaboration and find innovative solutions to accelerate Oligonucleotides.

Take advantage of this unique highly interactive meeting format designed for maximum engagement, collaboration, and networking.

Boston | Thursday 30th April 2026 | 08:00am - 17:10pm

VIEW AGENDA    REGISTER FOR FREE   OUR PARTNERS    EVENT INFORMATION

Why choose hubXchange?

FULL AGENDA

Click the topic titles to find out more!

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08:00
  1. Registration
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
08:30
  1. Opening Address & Keynote Presentation:
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
09:05
  1. Novel Modalities & Discovery
    60 mins
    • Novel Modalities & Discovery
  2. Drug Delivery
    60 mins
    • Drug Delivery
  3. CMC & Process Development
    60 mins
    • CMC & Process Development
    Analytical techniques, considerations and gaps supporting oligonucleotide and oligonucleotide-conjugate drug development Method development, validation & transfer challenges Impurity identification an ...
  4. Quality Control
    60 mins
    • Quality Control
    Framing the bottleneck: Align on the most common purification failure points after the generation of solid-phase synthesis crude and how they vary by oligo length, chemistry, and conjugation. Current ...
10:10
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
10:45
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
11:15
  1. Morning Refreshments
    10 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
11:25
  1. Novel Modalities & Discovery
    60 mins
    • Novel Modalities & Discovery
    How can early discovery teams better predict human translation for novel backbone chemistries and conjugation strategies? What preclinical models are most informative for de risking first in human stu ...
  2. Drug Delivery
    60 mins
    • Drug Delivery
    Which imaging modalities provide the most meaningful insight into tissue distribution and intracellular localization of oligonucleotides How can imaging data be correlated with pharmacology to disting ...
  3. CMC & Process Development
    60 mins
    • CMC & Process Development

    ChemGenes

  4. Quality Control
    60 mins
    • Quality Control
    How can QC strategies evolve to support increasing sequence diversity and chemical complexity in oligonucleotide and peptide pipelines What analytical gaps emerge during scale-up that are not apparent ...
12:25
  1. Networking Lunch
    60 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
13:25
  1. Spotlight Presentation: PolyPeptide
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
       
14:00
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
14:30
  1. 1-2-1 Meetings/Networking Break
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
15:00
  1. Afternoon Refreshments
    10 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
15:10
  1. Spotlight Presentation:
    30 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control
15:45
  1. Novel Modalities & Discovery
    20 mins
    • Novel Modalities & Discovery
    The search for therapeutic nucleic acids has historically been dominated by serendipity and high-throughput screening approaches. However, the combinatorial explosion of both sequence and chemical spa ...

    Nostrum Bio

  2. Drug Delivery
    20 mins
    • Drug Delivery
    Delivery remains the primary barrier to expanding oligonucleotide and peptide therapeutics beyond well validated tissues. This session will focus specifically on cross modality delivery approaches, wh ...
  3. CMC & Process Development
    20 mins
    • CMC & Process Development
    Extrahepatic oligonucleotide programs introduce distinct CMC challenges that differ from established liver targeted platforms. This session will examine manufacturing considerations specific to extrah ...
  4. Quality Control
    20 mins
    • Quality Control
    This session will focus specifically on the role of automation and digital systems in improving consistency, throughput, and scalability in oligonucleotide manufacturing. Key challenges include integr ...
16:10
  1. Novel Modalities and Discovery
    60 mins
    • Novel Modalities & Discovery
    On the evolutionary path: What's been done so far in optimizing naturally occurring ligands (GLP-1 drugs are a good example) Moving beyond the evolutionary sample: Generative design approaches that ca ...
  2. Drug Delivery
    60 mins
    • Drug Delivery
    Beyond hepatic delivery with GalNAc, what ligand technologies hold the most promise (e.g. antibodies, peptides, lipids, etc) to unlock new tissues/cell types? Where do you see the largest space for op ...
  3. CMC & Process Development
    60 mins
    • CMC & Process Development
    Overview of current and advanced delivery technologies such as LNP, AAV, conjugations, polymeric etc. for oligonucleotides CMC consideration and challenges associated with each delivery technologies R ...
  4. Quality Control
    60 mins
    • Quality Control
    How can QC teams detect and quantify raw material and intermediate variability before it impacts critical quality attributes of the final product What analytical controls are most effective for monito ...
17:10
  1. Evening Drinks Reception
    60 mins
    • Novel Modalities & Discovery
    • Drug Delivery
    • CMC & Process Development
    • Quality Control

 

EVENT INFORMATION

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DATES

Boston
30 April 2026
Thursday 30th April 2026

 

Hilton Woburn Hotel

VENUE

Hilton Munich Airport Hotel

2 Forbes Rd
Woburn
MA 01801
United States

MAP

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EVENT PARTNERS

REGISTRATION FORM

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Complimentary Registration is only available for Senior Scientists & above, in Pharma & Bio Tech, with an active drug pipeline.
 

For Service Providers, please click here.