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CNS Therapeutics Xchange - San Francisco 2026

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Welcome to hubXchange's CNS Therapeutics Xchange San Francisco 2026.

This event brings together senior-level scientists and executives from the pharmaceutical and biotech sectors to tackle key challenges in Target Discovery, Biomarkers, Blood Brain Barrier,  Preclinical Models and Clinical Development

Attendees can engage in roundtable discussions, pre-booked 1:1 meetings, presentations, and networking sessions with top industry experts, to foster collaboration and find innovative solutions to accelerate CNS Therapeutics.

Take advantage of this unique highly interactive meeting format designed for maximum engagement, collaboration and networking.

San Francisco | Thursday 10th September 2026 | 08:00am - 05:45pm

VIEW AGENDA    REGISTER FOR FREE    OUR PARTNERS    EVENT INFORMATION

Why choose hubXchange?

 

FULL AGENDA

Click the topic titles to find out more!

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08:00
  1. Registration
    30 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
08:30
  1. Opening Address & Keynote Presentation:
    30 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
09:05
  1. Target Discovery
    Innovating approaches to measure target engagement in the CNS
    60 mins
    • Target Discovery
    Russ Lebovitz
    Russ Lebovitz, Chief Executive Officer - Amprion Inc.
  2. Biomarkers
    Disease heterogeneity as a barrier to reliable biomarker development in CNS therapeutics
    60 mins
    • Biomarkers
    Jeremy Linsley
    Jeremy Linsley, Co-Founder/CSO - Stealth Mode Biotech
  3. Blood Brain Barrier
    The emerging receptor and transporter target landscape for drug delivery across the BBB ' lessons learned and translational status
    60 mins
    • Blood Brain Barrier
    Robert Thorne
    Robert Thorne, Denali Fellow - Denali Therapeutics
  4. Preclinical Models
    Overcoming the translational gap between preclinical CNS models and human outcomes
    60 mins
    • Preclinical Models
    Tao Huang
    Tao Huang, President & Chief Executive Officer - NeuCyte
  5. Clinical Development
    Why CNS clinical trials fail: Addressing the high attrition rates in neurological drug development
    60 mins
    • Clinical Development
10:10
  1. 1-2-1 Meetings / Networking Break
    30 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
10:40
  1. 1-2-1 Meetings / Networking Break
    30 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
11:10
  1. Morning Refreshments
    10 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
11:20
  1. Target Discovery
    Bridging omics discoveries with functional target validation in the brain
    60 mins
    • Target Discovery
  2. Biomarkers
    Ensuring reproducibility in CNS biomarkers: Overcoming the standardization and validation gap
    60 mins
    • Biomarkers
  3. Blood Brain Barrier
    Optimizing CNS penetration while minimizing systemic toxicity
    60 mins
    • Blood Brain Barrier
  4. Preclinical Models
    Capturing human neural circuitry complexity in disease modeling
    60 mins
    • Preclinical Models
     
  5. Clinical Development
    Defining meaningful clinical endpoints for CNS disorders: Beyond traditional rating scales
    60 mins
    • Clinical Development
12:20
  1. Networking Lunch
    60 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
13:25
  1. Spotlight Presentation:
    30 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
14:00
  1. 1-2-1 Meetings / Networking Break
    30 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
14:30
  1. 1-2-1 Meetings / Networking Break
    30 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
15:05
  1. Target Discovery
    Poster Presentation: Addressing disease heterogeneity in neurodegenerative and psychiatric target discovery
    30 mins
    • Target Discovery
  2. Blood Brain Barrier
    Poster Presentation: Evaluating the translational impact of nanotechnology and advanced carriers
    30 mins
    • Blood Brain Barrier
  3. Preclinical Models
    Poster Presentation: Tackling species differences to improve neurobiological model accuracy
    30 mins
    • Preclinical Models
  4. Clinical Development
    Poster Presentation: Tackling species differences to improve neurobiological model accuracy
    30 mins
    • Clinical Development
15:35
  1. Afternoon Refreshments
    10 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development
15:45
  1. Target Discovery
    Validation strategies for novel CNS targets: From molecular mechanism to therapeutic candidate
    60 mins
    • Target Discovery
  2. Biomarkers
    Detecting the undetectable: Tackling low abundance and sensitivity challenges in CNS biomarker measurement
    60 mins
    • Biomarkers
  3. Blood Brain Barrier
    Targeting delivery of gene therapies for CNS indications
    60 mins
    • Blood Brain Barrier
  4. Novel Modalities
    Why over-reliance on rare genetic mutation models is misleading sporadic CNS drug discovery
    60 mins
    • Preclinical Models
  5. Clinical Development
    Managing the placebo effect: A persistent challenge in CNS clinical trial design
    60 mins
    • Clinical Development
16:45
  1. Evening Drinks Reception
    60 mins
    • Target Discovery
    • Biomarkers
    • Blood Brain Barrier
    • Preclinical Models
    • Clinical Development

EVENT INFORMATION

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DATES

San Francisco
Sept 10, 2026

Thursday 10th September 2026

 

DoubleTree by Hilton San Francisco Airport Hotel Photo

 

VENUE

 

DoubleTree by Hilton San Francisco Airport Hotel

DoubleTree by Hilton
San Francisco Airport Hotel
835 Airport Blvd, Burlingame
California, 94010-9949

MAP

EVENT PARTNERS

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EVENT PARTNERS

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REGISTRATION FORM - Register for free!

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Complimentary Registration is only available for Senior Scientists & above, in Pharma & Bio Tech, with an active drug pipeline.
 

For Service Providers, please click here.

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