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Welcome to hubXchange's Antibody Therapeutics Xchange Boston 2024.

This event brings together senior-level scientists and executives from the pharmaceutical and biotech sectors to tackle key challenges in Target Selection, Lead Identification & Optimization, Formats & Scaffolds, Bi/Multispecifics and Emerging Technologies.

Attendees can engage in roundtable discussions, pre-booked 1:1 meetingspresentations, and networking sessions with top industry experts, to foster collaboration and find innovative solutions to accelerate antibody therapeutics.

Take advantage of this unique highly interactive meeting format designed for maximum engagement, collaboration and networking.

Boston | Monday 17th June 2024 | 08:00am - 06:45pm

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FULL AGENDA

Click the topic titles to find out more!

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08:00
  1. Registration
    Grand Foyer
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
10:10
  1. 1-2-1 Meetings/Networking Break
    1-2-1 Meetings (Salon E/G) | Networking Break (Grand Foyer)
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
10:40
  1. 1-2-1 Meetings/Networking Break
    1-2-1 Meetings (Salon E/G) | Networking Break (Grand Foyer)
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
11:10
  1. Morning refreshments
    Grand Foyer
    10 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
11:20
  1. Lead Identification & Optimization
    What are the considerations for successful lead identification & optimization in biotherapeutic antibody discovery?
    Salon B
    60 mins
    • Lead Identification & Optimization
    Integrated antibody discovery mindset based on biotherapeutic MOA is critical. How to choose lead identification and optimization platforms? You get what you screen for! The importance of screening as ...
  2. Bi/Multispecifics
    Technologies accelerating engineering into advanced modalities
    Salon D
    60 mins
    • Bi/Multispecifics
    Common Light Chain discovery approaches, advantages, and limitations Single Domain Antibodies: what we have learned so far about VHHs, discovery platforms, reformatting, physicochemical properties Bi- ...
  3. Emerging Technologies
    Antibody selection for complex membrane targets
    Salon F
    60 mins
    • Emerging Technologies
    Antibody discovery vs complex antigens that cannot be easily purified remains a challenge. Does the lack of available material limit the targets that are pursued? Would a consistent source of properly ...
12:20
  1. Networking Lunch
    Thomson Hall - First Floor
    60 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
13:25
  1. Spotlight Presentation: Innovative Production and Engineering Strategies for Fab, ScFv & VHH
    Salon H
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
    Antibody fragments like Fab, ScFv, and VHH are emerging stars in antibody drug development, utilized both as standalone molecules and as building blocks of bispecific antibodies. However, their produc ...
13:55
  1. 1-2-1 Meetings/Networking Break
    1-2-1 Meetings (Salon E/G) | Networking Break (Grand Foyer)
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
14:25
  1. 1-2-1 Meetings/Networking Break
    1-2-1 Meetings (Salon E/G) | Networking Break (Grand Foyer)
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
15:00
  1. Spotlight Presentation: Engineering Unique Properties in Next-Gen Antibody Therapies
    Salon H
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
    We will explore some of the cutting-edge advancements in our antibody discovery and engineering approaches to engineer unique properties in next generation therapeutic antibodies. With the aim to enha ...
15:30
  1. 1-2-1 Meetings/Networking Break
    1-2-1 Meetings (Salon E/G) | Networking Break (Grand Foyer)
    30 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
16:00
  1. Afternoon refreshments
    Grand Foyer
    10 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies
16:10
  1. Target Selection
    Poster Presentation: Pioneer Platform: A Novel Biotherapeutic Antibody Discovery Platform [Lead Identification & Optimization Topic]
    Salon A
    30 mins
    • Target Selection
    The PioneerTM Antibody Discovery Platform is Bio-Rad’s new service for biotherapeutic lead generation. The new Pioneer Antibody Library is central to the Discovery Platform. Its design is informed by ...
  2. Bi/Multispecifics
    Poster Presentation: Antibody Discovery Dead Ends and New Approaches: The Power of Polyclonal Sequencing [Emerging Technologies Topic]
    Salon D
    30 mins
    • Bi/Multispecifics
    We will explore some of the cutting-edge advancements in our antibody discovery and engineering approaches to engineer unique properties in next generation therapeutic antibodies. With the aim to enha ...
  3. Emerging Technologies
    Poster Presentation: Accelerating the characterization of the binding mode of an antibody against its target with a novel AI-MM pipeline
    Salon H
    30 mins
    • Emerging Technologies
    The computational development of antibodies is an emerging industry that has become feasible thanks to the recent boom in artificial intelligence. Here, we want to present our recent advances in antib ...
  4. Lead Identification & Optimization
    Poster Presentation: Maximizing VHH lead generation for therapeutic breakthroughs
    Salon B
    30 mins
    • Lead Identification & Optimization
    VHHs, the variable domains of camelid heavy chain-only antibodies, are gaining significant attention due to their unique advantages, including their ability to bind hidden epitopes and their adaptabil ...
    Poster Presentation by Immunoprecise Antibodies
  5. Formats & Scaffolds
    Poster Presentation: AlivaMab' Platforms for Discovery and Engineering for Bispecifics and Advanced Modalities Jane Seagal, Vice President, Antibody Discovery, Ablexis and AlivaMab Discovery Services [Bi/ Multi Specifics Topic]
    Salon C
    30 mins
    • Formats & Scaffolds
    Biologics have become the top-selling class of therapeutics that continue to grow as new drugs are approved for an array of disease areas. Ablexis and AlivaMab Biologics have developed a versatile too ...
    Poster Presentation by Ablexis and AlivaMab Discovery Services
16:45
  1. Target Selection
    Salon A
    60 mins
    • Target Selection
    What does a protein engineer bring to the table when selecting therapeutic targets? What are new or emerging bioinformatic databases for target ranking? Tips on Tabs/Lens.org mining to generate tool m ...
  2. Lead Identification & Optimization
    Salon B
    60 mins
    • Lead Identification & Optimization
    Agonistic antibodies to checkpoint inhibitors – how to select the best epitope and achieve engagement in the immune synapse? Agonistic bispecific antibodies to cytokine receptors – how to achieve spec ...
  3. Bi/Multispecifics
    Salon D
    60 mins
    • Bi/Multispecifics
    Can bi- or multi-specifics approaches revitalize known targets? Balancing the target affinities and expression levels on relevant cell types How to navigate the complex landscape of available bi-speci ...
  4. Emerging Technologies
    Salon F
    60 mins
    • Emerging Technologies
    Disease complexity, e.g. causality, heterogeneity, targetability, etc Drug discovery efficiency, e.g. vast space, druggability/property/manufacturability, specific targeting/delivery, etc
17:45
  1. Drinks-Canape Reception
    Grand Foyer
    60 mins
    • Target Selection
    • Lead Identification & Optimization
    • Formats & Scaffolds
    • Bi/Multispecifics
    • Emerging Technologies

 

EVENT INFORMATION

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DATES

Boston
June 17, 2024

Monday 17th | 08:00am - 06:45pm

VENUE

Hilton Hotel Woburn/Boston

Hilton Boston/Woburn
2 Forbes Road
Woburn MA
01801

MAP

EVENT PARTNERS