Asymchem’s oligonucleotide technology capabilities provide clients with full services in drug substance, from process development through GMP manufacturing, and drug product, from pre-formulation development through fill-finish. The process chemistry, analytical, formulation, and regulatory teams collaborate to provide clients with a fast, efficient, and flexible integrated solution for oligonucleotide development and manufacturing.

Our oligonucleotide platforms are equipped with advanced technologies including GE ÄKTA oligonucleotide solid-phase synthesizer and purification equipment from gram to kg-scale. In addition, analytical equipment including Q-TOF, UPLC-MS, UPLC, GPC, and other instruments can provide support for oligonucleotide structure characterization, analytical method development and validation, final product release testing, and stability research