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Advancing a First-in-Class Small Molecule Targeting Creatine-Dependent Thermogenesis

26 Sep 2025
Translational & Clinical Strategy
  • This first-in-class small molecule activates the creatine-driven thermogenic pathway, offering a novel mechanism of action distinct from traditional metabolic targets.
  • Translational strategy highlights key milestones in preclinical efficacy, safety profiling, and biomarker development to support clinical entry
  • The program exemplifies efficient lab-to-clinic progression through integrated discovery, mechanism validation, and early regulatory alignment
Industry Expert
Maria Garat, Chief Executive Officer - Eolo Pharmaceuticals