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Beyond the Sequence: Solving Design & Delivery Challenges for Next-Gen Therapeutic Modalities

26 Sep 2025
 Innovation in Therapeutic Modalities
  • How can we effectively integrate the design of oligonucleotides, small molecules, and conjugates into unified therapeutic strategies?
  • What are the key challenges and solutions for achieving tissue- and cell-specific delivery, particularly for CNS and intracellular targets?
  • How can we balance efficacy and safety in complex modalities, especially when managing dose, off-target effects, and immune responses?
  • In what ways can high-resolution RNA and protein structural insights be leveraged to optimize potency and specificity?
  • How can collaborative innovation models that unite biology, chemistry, and AI accelerate therapeutic discovery?
Industry Expert
Allen Shen, Founder - XAIGene Biotechnology