Novel Therapeutic Modality: Endogenous Circular DNAs in Human Cells
26 Sep 2025
Innovation in Therapeutic Modalities
- Circular DNA exists as an endogenous molecule in human cells with emerging relevance to health and disease.
- Circular DNA contributes to pathological processes, including chemotherapy resistance in cancer, immune response, microbiome, and aging.
- Holds promise for both therapeutic and diagnostic applications.
- Synthetic circular DNAs have been used as donor templates for CRISPR-based therapeutics and as gene therapy vectors.
Industry Expert
