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Next-Generation Oligonucleotides: Creative Strategies for Molecule Design and Targeted Delivery

02 Dec 2025
Drug Delivery
  • Enhancing efficacy and stability with novel oligonucleotide modifications and chemistries
  • Beyond target mRNA KD: Diversifying oligo modalities and Mode of Actions
  • Leveraging d AI/machine learning for increased oligonucleotide potency and safety
  • Improved tissue and cell-type specific delivery though advanced conjugation and formulation strategies
Industry Expert
Kerstin Hofer, Science and People Lead - Roche