This session on the Manufacturing Track will cover the use of untargeted mass spectrometry for oligonucleotide analytics. It will focus on how this general technique improves accuracy and quality in oligonucleotide production by identifying key molecular components and impurities. The session will explore its role in streamlining manufacturing processes and ensuring precision and consistency in oligonucleotide-based research and development. The discussion will highlight the importance of using this tool for enhancing quality control and advancing oligonucleotide manufacturing in various applications.