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Immune metabolic pathways in maintaining tolerance

25 Sep 2025
Immune Regulation
  • Recent advances in our understanding of immune cell metabolic pathways, and their driving role in inflammatory & autoimmune disease.
  • Difficulties and barriers to translating preclinical work on immunometabolism to new therapies (training, tool access, and consensus on experimental models).
  • Disconnect between in vitro models and in vivo immunometabolism.
  • Learning from existing anti-inflammatory drugs targeting immune metabolic pathways.
  • Moving beyond drugging immunometabolism with small molecules: new therapeutic modalities & delivery technologies on the horizon.
  • Opportunities for targeting immunometabolism beyond anti-inflammatory therapeutics: improving efficacy of cell therapies, overcoming immune suppression in cancer, and targeting “fibrometabolism” in fibrotic disease.
Industry Expert
Greg Timblin, CEO & Co-Founder - Inapill