Skip to main content
Loading
Shyam Sarikonda

Shyam Sarikonda

Director, Translational Sciences, Legend Biotech
Scientific Leader in Immuno-Oncology and Cell & Gene Therapy Drug Development. Trained immunologist with expertise in translational research and preclinical and clinical biomarker development for CAR-T, Immuno-oncology and small molecule therapies for Phase I/II or III clinical trials. Advanced R&D goals through collaboration with KOLs leading to multiple peer reviewed manuscripts. Led the publication of cross-industry white paper in CAR-T immune monitoring. Mentored multiple associates in efficiently managing projects to achieve time- and business-critical goals. Evaluated and implemented new technologies for scientific advancements (e.g., HPFC) and laboratory automation solutions (Liquid handlers) as well as data analysis (AI based flow cytometry data analysis). Championed the development, validation and implementation (under GXP regulations) of multiple biomarker monitoring panels (>30) in AML/CLL/MM/AML and DLBCL etc., disease settings. Proficient at business development project proposals and portfolio prioritization. Experienced in regulatory document submissions including BAR/BDR and briefing books.