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Paul Ponath - Bolt Biotherapeutics

Paul Ponath

Director, Bolt Biotherapeutics

Paul Ponath is an immunologist with more than two decades of leadership experience in the discovery and development of innovative therapeutics across oncology, autoimmune, and inflammatory diseases. He has built a distinguished career advancing novel biologics from early discovery through translational development, with expertise in antibody-based therapeutics, antibody-drug conjugates (ADCs), and immune-modulating platforms. Paul has extensive experience in the development of next-generation antibody therapeutics, including Fc-engineered antibodies, bispecific antibodies, T-cell engagers, and ADCs incorporating both cytotoxic and immune-stimulating payloads. Most recently, Paul served as Co-Lead of Payload Discovery and Platform Development at Bolt Biotherapeutics.

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