Opening Address & Keynote Presentation: Translational Applications of Molecular and Functional Imaging In Optimisation of the Drug Discovery Pipeline
24 Jun 2024
Salon H
Drug Delivery
,
Novel Targets
,
Preclinical
,
Clinical Studies
)
The application of imaging techniques to evaluate receptor binding and therapeutic drug-target occupancy in the living brain is a powerful tool in drug discovery. Here, we share an overview of the application of nuclear and functional imaging modalities to support translational studies to evaluate:
- Therapeutic compound CNS biodistribution applications for small and large candidate molecules.
- Current tools to evaluate dose-occupancy study applications in the CNS.
- Pharmacodynamic outcome measures in the absence of direct imaging measures.
- Considerations for a novel radioligand development pathway.
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