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Sponsor Led Roundtable: Histology and IHC in CNS Drug Discovery: 2D or 3D? [Preclinical Topic]

24 Jun 2024
Salon A
Novel Targets
Sponsor Led Roundtable: Histology and IHC in CNS Drug Discovery: 2D or 3D? [Preclinical Topic]
  • How does your team use histology and IHC in their drug discovery efforts and are there any bottlenecks or gaps?
  • For therapeutics with complex biodistribution patterns (cell/gene/biologic), is sampling the brain with slice IHC sufficient or would complete staining of the intact brain be beneficial and under what circumstances
  • What are the challenges with image data viewing, archiving, analysis and transmission?
  • How much of your histology and IHC work needs GLP designation?
  • What role for 3D IHC could you conceive of over traditional thin section staining?
Industry Expert
Damian Wheeler, CEO - Translucence Biosystems