Overcoming the translational gap between preclinical CNS models and human outcomes
05 May 2026
Disease Models
- What are the appropriate scaling factors from preclinical models to humans, and what factors should be taken into account (e.g., brain volume, CSF, body size, etc.)?
- What are the differences in CSF flow between preclinical models and humans?
- What are the differences in the distribution of cell types in the brain between preclinical models and humans?
- Why is there a lack of good in vitro models?
