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Engineering bispecific ADCs: How to select target pairs, format, conjugation, and DAR

02 Sept 2026
ADC Linker Design & Conjugation Technologies
  • Can "unclean" targets be opened up through AND-gating?

  • Can OR-gating address tumor heterogeneity?

  • Can poor-internalizing targets be opened up via bispecifics?

  • How should linker and DAR selection change for bispecifics?

Industry Expert
Shaun Lippow, Head of Biologics - Remunix, Inc.