Engineering bispecific ADCs: How to select target pairs, format, conjugation, and DAR
02 Sept 2026
ADC Linker Design & Conjugation Technologies
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Can "unclean" targets be opened up through AND-gating?
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Can OR-gating address tumor heterogeneity?
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Can poor-internalizing targets be opened up via bispecifics?
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How should linker and DAR selection change for bispecifics?
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