Artificial intelligence (AI) is transforming antibody discovery and engineering. Ailux's platform synergistically combines the best of our comprehensive wet lab, AtlaX biologics database, and three proprietary AI engines. We will explore our latest case studies that exemplify our AI-driven approach for tackling challenging targets, identifying unique functional antibodies, and achieving multi-objective optimization. This presentation provides our realistic and evidence-based perspective on AI’s impact on developing next-generation antibody therapeutics.