Sponsor Poster Presentation: Solving the Bispecific Antibody Mispairing Challenge in Preclinical R&D
19 Feb 2025
Bi/Multispecifics
Efficient bispecific antibody (bsAb) production requires precise assembly of multiple chains. Combining the knob-into-hole (KiH) mutation set with Lonza’s bYlok® bsAb pairing technology, evitria AG achieves >95% heterodimer purity and <5% aggregation using a single Protein-A purification step. Further, proprietary, in-house ion exchange (IEX) chromatography further streamlines polishing for applications beyond early R&D, including large-scale animal studies. Leveraging 15 years and over 130,000 protein production runs, evitria AG offers rapid development of diverse, high-quality bsAb panels.
Industry Expert