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Key considerations in designing ADCs to minimize resistance development

19 Feb 2025
Antibody Drug Conjugates
  • What are the key considerations for target selection to enhance ADC efficacy?
  • What should be the payload and linker strategy to minimize resistance initiation?
  • How to monitor and manage resistance (including combination strategy and targeting multiple pathways)?
  • Should we be considering patient stratification to minimize resistance development? 
Industry Expert
Bishnu Nayak, Senior Director and Site Head - NeologicsBio