Spotlight Presentation: Neochromosome’s Antibody ToolkitTM: How a ‘Switchable’ Yeast, Antibody Libraries and Laboratory Robotics Enable High Throughput Hit Characterization
14 Apr 2025
Bi/Multispecifics
Formats & Scaffolds
Lead Identification & Optimization
Target Selection & Mechanisms of Action
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neoSwitch is a yeast strain with the capacity to ‘switch’ between surface display and secretion, removing the need for a reformatting step before initial hit characterization. Antibody fragments are secreted at high titers in multi-well plates and the raw supernatant is compatible with biolayer interferometry. When combined with the Opentrons Flex, neoSwitch enables turnkey automation of key workflows, including protein purification.
Industry Expert
