Enhancing antigen-specific binding affinity for improved clinical efficacy
14 Apr 2025
Target Selection & Mechanisms of Action
- Affinity maturation to enhance the binding affinity of therapeutic monoclonal antibody (mAb).
- Development of anti-carcinoma mAbs targeting O-glycans.
- Mechanisms of action of therapeutic anti-cancer mAbs primarily focus on stimulation of various innate effector processes and/or inhibiting specific signaling pathways
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