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Developability / manufacturability of bispecifics

14 Apr 2025
Bi/Multispecifics
  • Which developability assays are most informative for assessing candidates early on? -for stability, PK, high-concentration, immunogenicity, specificity, etc
  • What are the most impactful in silico methods, and how reliable are they?
  • What is the impact of various bispecific/multispecific antibody formats on developability and manufacturability?
  • How does the assessment of bispecific/multispecific antibodies differ from mAbs when interpreting developability assay results?
Industry Expert
Joel Goldstein, Senior Director R&D - Celldex Therapeutics