Designing T-cell engagers for targeting pMHC
03 Nov 2026
Formats & Scaffolds
- How have intracellular proteins historically been accessed by antibody therapeutics?
- How can intracellular proteins, when presented as pMHC, be targeted by TCR and TCR-mimicking antibody-based therapeutics?
- What are suitable architectures for pMHC-targeting T-cell engagers (TCEs)?
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