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What is the perfect workflow for generating antibody drug candidates?

28 Oct 2024
Lead Identification & Optimization
What is the perfect workflow for generating antibody drug candidates?
  • How many hits (binders) should be further analyzed? 
  • How to select candidates of interest? Which parameters are highly relevant? 
  • Developability assessment early on as a selection criterion or rather later for a smaller number of candidates? 
  • What are the main challenges: affinity, correct epitope, developability, pH specific binding, posttranslational modifications/mutations, challenging targets, functionality?
Industry Experts
Birthe Jessen-Park, Technical Sales Specialist Custom Antibodies - Bio-Rad