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How to design ADCs to avoid development of resistant clones?

28 Oct 2024
Antibody Drug Conjugates
  • Target selection: Can we identify cancer-specific targets so critical to tumor cell function that cancer cells cannot live without them?
  • Antibody Selection: Can we identify critical epitopes on our targets and select antibodies against them?
  • Multi-epitope approaches: Can we direct ADCs to more than one epitope on our targets?
  • Multi-target approaches: Can we combine ADCs to hit multiple targets simultaneously? Or sequentially? What about multivalent ADCs?
Industry Experts
Michael Lebowitz, Vice President of Research - Athanor Biosciences