How to design ADCs to avoid development of resistant clones?
28 Oct 2024
Antibody Drug Conjugates
- Target selection: Can we identify cancer-specific targets so critical to tumor cell function that cancer cells cannot live without them?
- Antibody Selection: Can we identify critical epitopes on our targets and select antibodies against them?
- Multi-epitope approaches: Can we direct ADCs to more than one epitope on our targets?
- Multi-target approaches: Can we combine ADCs to hit multiple targets simultaneously? Or sequentially? What about multivalent ADCs?
Industry Experts