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Opportunities and Challenges of using single domain antibodies in novel multifunctional biologics

18 Nov 2024
Formats & Scaffolds
  • Single domain antibodies are incredibly versatile and increasingly appear in clinical pipelines. What are the main drawbacks for the development of these domains as novel therapeutics?
  • In multifunctional biologics, what are the drivers to select single domain vs classical antibody formats?
  • In which areas can single domain antibodies make the difference vs conventional antibodies? What are the key drivers for their success? In which areas do they fail to meet up to more classical antibody formats?
  • Beyond classical purified biologics, what are the opportunities of using single domain antibodies for alternative delivery modes?
Industry Expert
Tom Van Bogaert, Distinguished Scientist | Innovation Area Head - Sanofi