Lead Identification & Optimisation topic: Preventing late-stage failures: Can AI improve antibodies' affinity and developability — early?
28 Apr 2026
ADC Cytotoxic Payload
- At what stage in lead optimization does AI create the most value - affinity maturation, developability optimization, cross reactivity?
- How much data is truly needed to train predictive models for a single antibody campaign?
- Can we reliably predict developability liabilities (aggregation, polyspecificity, self-association) before experimental screening?
- How do we validate AI-generated candidates in a way that builds organizational trust?
- How useful would a no code computational tool be for experimental scientists?
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