Emerging therapeutic concepts and progress based on bi/multispecifics
28 Apr 2026
Bi/Multispecifics
- How can cell-surface target degraders be engineered to achieve efficient internalization and sustained target depletion without compromising specificity or safety?
- What strategies enable recycling and sweeping antibodies to overcome antigen accumulation while maintaining favorable PK/PD and manufacturability?
- How can BBB penetration shuttles balance transport efficiency, target engagement, and systemic exposure to safely deliver antibody therapeutics to the CNS?
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