A discussion of strategies for reducing on-target / off-tumor toxicity
18 Jun 2025
Toxicity & Off-Target Effects
- What are the key antibody design considerations to maximize tumor delivery?
- How can bispecific targeting enhance payload delivery and/or tumor specificity?
- What linker-payload factors should be considered when targeting the tumor microenvironment?
- Which special organs should be of concern, and what specific factors should be monitored?
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