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High-dimensional data needs a metadata ontology to multiply AI leverage

09 Sept 2026
Data Quality
  • What is your individual role with data and what are the main categories of data you plan to expose to AI in the upcoming year?
  • Share an example of where you've seen data used out-of-context in a meta-analysis for instance, leading to misleading conclusions. 
  • In your field, what are your guiding principles for distinguishing poor quality data that should be ignored versus acceptable quality without a presently digestible interpretation?
  • On your team, how do you delegate the responsibilities for data labeling (clinical metadata, assay conditions, instrument settings, quality control).
  • How does your organization handle the various stakeholder opinions regarding metadata terminology and hierarchy?  Is there an ontology editing process that works efficiently?
  • When querying data from a lake for AI interpretation, how do your data scientists document that data with synonymous search terms have been included?  How do they document what quality thresholds (if any) were respected?
  • Looking ahead, what will make the biggest difference in enabling AI to turn high-dimensional data into real medicines: QC, labeling, ontology-assisted LLMs, ...?
Industry Expert
Todd DeSantis, Vice President of Bioinformatics - Resilient Biotics