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Efficacy and safety considerations for IPSC-derived cell therapies

15 Apr 2025
Cell Therapy Development
  • What preclinical characteristics are most convincing that an IPSC-derived cell therapy will be optimally efficacious in the clinic?
  • What approaches are being employed for clinical safety regarding tumorigenicity, immunogenicity and genetic instability  in IPSC-derived cell therapies?
  • Compared with autologous cell therapies or other therapeutic modalities, what advantages/disadvantages do IPSC-derived cell therapies possess?
  • Where do you see the next-generation IPSC-derived cell therapies going to enhance efficacy and safety of the current generation? 
Industry Expert
Jill Carton, Vice President, Synthetic Biology - Century Therapeutics