Upstream strategies to reduce empty capsid formation
04 May 2026
Gene Therapy Manufacturing
- Which upstream design and process levers have the greatest impact on improving packaging efficiency and reducing empty capsids?
- How do different production platforms fundamentally influence capsid assembly, genome encapsidation, and consistency at scale?
- What trade-offs have you observed between yield, quality, and packaging efficiency when optimizing upstream processes?
- Which real-time or near–real-time in-process analytics are truly actionable for controlling empty capsid formation?
- How are teams using in-process data to adjust timing, conditions, or harvest strategies before empty capsids become unavoidable?
Industry Expert
