End to End Functional Closure of Cell Therapies; All Things Considered
24 Jun 2025
Cell Therapy Development
- Evaluate the current state of functional closure across key unit operations in cell therapy manufacturing — from apheresis to fill-finish
- Identify the major technical and regulatory gaps preventing full closure and where innovation is still required
- Discuss best practices and emerging solutions for integrating functionally closed systems (e.g., automated manufacturing platforms, closed-system cell washes, media fills, final formulation)
- Explore the role of GMP-compliant ancillary materials — including Akron’s work on prefilled, closed-system bags — in enabling seamless tech transfer and scale-up
- Share lessons learned from early-stage to commercial-stage manufacturing efforts to fully close the process end to end
Industry Expert
